ANTAGONISM BETWEEN MES-4 AND POLYCOMB REPRESSIVE COMPLEX 2 PROMOTES APPROPRIATE GENE EXPRESSION IN C. ELEGANS GERM CELLS

The Caenorhabditis elegans MES proteins are key chromatin regulators of the germline.MES-2, MES-3, and MES-6 form the C.elegans Polycomb repressive complex 2 Buckle and generate repressive H3K27me3.MES-4 generates H3K36me3 on germline-expressed genes.Transcript profiling of dissected mutant germlines revealed that MES-2/3/6 and MES-4 cooperate to p

The role of uropathogenic Escherichia coli (UPEC) in colonization and infection of female patients with anatomical and functional abnormalities of the urinary system is elusive.In this study, the PURE BLACK CHERRY phenotype, genotype and the phylogeny of UPEC strains isolated from the urine of pediatric female patients with cystitis of normal and a